Resistance to steam sterilization is an important consideration for the selection of polymeric adhesives, sealants and potting compounds for use in medical applications. Autoclaving is one of the most rigorous and widely employed sterilization methods for medical devices. With this in mind, Master Bond has developed a wide variety of products for this purpose. Many compounds have been successfully tested for the U.S. Pharmacopeia (USP) Class VI requirements, and some select systems among them can withstand repeated autoclaving exposure.

The following graphs display the autoclave resistance of many diverse Master Bond products. The products were cast into molds to create a size roughly of 2 inches in diameter, and 0.125 inches thick. These castings were then subjected to multiple autoclaving cycles up to 100 cycles. Each autoclave cycle was around 20 minutes at 250 F (~ 121°C) and about 15 psi of steam pressure. The weight change was then measured periodically, which is illustrated in the graph. As shown in the graphs below, there is a reference epoxy, which gains much more weight compared to the other epoxies below, which have far superior resistance to weight gain.

Autoclaving resistance of EP62-1Med

Autoclaving resistance of EP30Med

Autoclaving resistance of EP3HTMed

Autoclaving resistance of UV15DC80Med

Autoclave resistance results of Master Bond epoxy EP42HT-2Med

Autoclave resistance results of Master Bond epoxy EP42HT-4AOMed Black

Autoclaving resistance of  UV10TKMed

Autoclaving resistance of EP46HT-2Med

It must be noted that in selecting the right product for repeated autoclaving in your medical device, there are many other factors involved. For more information on Master Bond products, please contact our technical advisors.

Disclaimer: TheEP42HT-4AOMedBlack findings in this article are not meant to be used for specification purposes.

Adhesives for Autoclave Resistance

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