Biocompatible Adhesives, Sealants and CoatingsUSP Class VI approved one and two component adhesives, sealants and coatings are formulated for the assembly of medical devices. These specialty compounds are designed to adhere to dissimilar substrates, resist exposure to sterilization and for easy application.

Key Advantages of Master Bond's Biocompatible Compounds

Medical grade adhesives, sealants, coatings and potting/encapsulation compounds need to be non-toxic and show compatibility with blood and body fluids. Additionally, they must be biologically inert. There are two standard tests used to determine their suitability: U.S. Pharmacopeia (USP) Class VI and/or ISO 10993. Master Bond offers biocompatible compounds, which meet one or both specifications.

General Comparison of Different Chemistries for Medical Device Adhesives

Overview: Epoxies and Silicones

Epoxies Silicones
1-part 2-part 1-part 2-part
Applications Bonding, coating, sealing
and potting
Bonding, coating, sealing
and potting
Bonding, coating, and sealing Bonding, coating, sealing
and potting
Typical Service
Temperature Range
4K to 400°F 4K to 400°F -75°F to 400°F -65°F to 400°F
Curing
Requirements
Fast cures at elevated temperatures Room/heat curing systems Room temperature (moisture) curing Room/heat (addition) curing systems
Key Properties Structural, with good temperature resistance and easy processing Excellent chemical resistance, with very good physical strength profile High degree of flexibility with no mixing needed Excellent flexibility, and cures in thick sections with low stress imparted

Overview: Other Chemistries

UV/LED Curing Systems Epoxy-Polyurethane Blends Cyanoacrylates
Applications Bonding, coating, sealing and encapsulation Bonding, coating, sealing and potting Bonding, coating, and sealing
Typical Service Temperature Range -60°F to 400°F 4K to 250°F -60°F to 250°F
Curing Requirements Light curing systems (-365 nm to 405 nm) Dual curing with heat Room/heat curing systems Room temperature curing systems
Key Properties Quick cure times, along with good optical as well as physical strength characteristics Good degree of toughness, combining flexibility with good overall physical strength properties Good bond strength capability with quick cures for smaller components

Bond Strength

Epoxies Silicones UV/LED Curing Systems Epoxy-Polyurethane Blends Cyanoacrylates
Metals Excellent Good Good Good Excellent
Plastics Excellent Fair Very Good Fair Very Good
Glass Very Good Good Very Good Good Very Good
Rubbers Very Good Fair Fair Good Good

Sterilization Resistance

Epoxies Silicones UV/LED Curing Systems Epoxy-Polyurethane Blends Cyanoacrylates
Repeated Autoclaving Excellent Poor Very Good Poor Poor
Repeated Chemical Sterilization (Sterrad®) Excellent Poor Very Good Poor Poor
Gamma, E-beam, EtO etc. Excellent Excellent Excellent Very Good Good
 

All systems can be applied manually, semi-automatically and automatically.

Sterrad® is a registered trademark of Johnson & Johnson.

Find out more about our full product line of USP Class VI approved adhesive systems.

Find out more about our products meeting ISO 10993-5 cytotoxicity requirement.

Most Popular USP Class VI Approved Products

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